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KMID : 0816120080110000149
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Korean Journal of Pediatric Gastroenterolology and Nutrition
2008 Volume.11 No. 0 p.149 ~ p.152
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Obesity-associated Morbidity
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Choi Kwang-Hae
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Abstract
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Obesity tracks from childhood into adulthood, and the persistence of obesity rises with age among obese children. Obesity are independent risk factors for increased morbidity and mortality throughout the lifecycle. Obese individuals develop resistance to the cellular actions of insulin, characterized by an impaired ability of insulin to inhibit glucose output from the liver and to promote glucose uptake in fat and muscle. Insulin resistance is a key etiological factor for type 2 diabetes mellitus, dyslipidemia, hypertension, nonalcoholic steatohepatitis, polycystic ovarian syndrome.
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KEYWORD
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Obesity, Insulin resistance, Morbidity
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